PT-141 (Bremelanotide) was originally developed from tanning analog Melanotan II. PT-141 is a targeted aphrodisiac that antagonizes receptors MC3 and MC4 in the hypothalamus.
PT-141 is the only synthetic aphrodisiac. The aphrodisiac effects of Bremelanotide are in a class of its own. Studies have shown Bremelanotide to be effective in treating sexual dysfunction in both men (erectile dysfunction or impotence) and women (sexual arousal disorder). Nine out of ten volunteers experienced sexual arousal in clinical trials. Unlike Viagra and other related medications (PDE5s - blood pushers), PT-141 acts upon the nervous system.